Leptin is the ‘satiety’ hormone produced by fat cells and it helps regulating energy balance by inhibiting hunger and it controls your metabolism. Leptin acts as the ‘opposite’ of ghrelin hormone (see my previous post).
How much leptin is released from the fat cells depends on how much fat there is: the more fat you have the more leptin is released.
Simply put: When your leptin levels increase, your brain sends a signal that you’re ‘full’ and your metabolic rate increases because of this signal. When leptin levels decrease, your brain sends a signal that you’re no longer ‘full’ and your metabolic rate decreases. The longer your body is in calorie deficit (hunger) the lower your leptin levels decrease and your metabolic rate slows down.
If you constantly eat above your maintenance calorie levels, you can become leptin resistant. The more leptin resistant your body becomes, the more fat you will store as your body will not be able to distinguish if your body fat levels are too high and the leptin receptors are desensitized.
How to maintain normal leptin levels:
* try and stay lean,
* don’t go on for too long to bulk,
* when you feel your metabolism slowed down, include a cheat meal/day. The excess calories will kickstart your leptin production (but only if you had calorie deficit beforehand for some time).

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